FaridabadBy Dr B.C. Gupta, MD · 2026-10-01
Ask the Pathologist - MCQ of the Week. A short question to test how well you know common laboratory tests, with a plain-English explanation from Dr B.C. Gupta, MD (Pathology).
Q. Which test examines a stained blood film under the microscope to find malaria parasites directly?
- A. Peripheral smear for malarial parasite (PS for MP)
- B. Erythrocyte sedimentation rate (ESR)
- C. HbA1c
- D. Thyroid profile
Answer: A. Peripheral smear for malarial parasite (PS for MP)
A peripheral smear for malarial parasite, also written as PS for MP, is a stained blood film examined under the microscope. The thick film is used to find whether parasites are present, and the thin film lets the pathologist identify the species and count how many red cells are infected. It is the traditional reference method for malaria, and it can tell Plasmodium falciparum apart from Plasmodium vivax, which matters because falciparum malaria can turn severe quickly.
A rapid malaria antigen test is also used and gives an answer in about fifteen to twenty minutes by detecting proteins made by the parasite. It is quick and does not need a microscopist, but it cannot give a parasite count and may remain positive for some days after treatment. For this reason it is often done alongside a smear rather than instead of one.
ESR, HbA1c and a thyroid profile do not detect malaria. ESR is a general marker of inflammation, HbA1c reflects average blood sugar over about three months, and a thyroid profile checks hormone levels. If your doctor has asked for a malaria smear or a PS for MP, call the centre to confirm preparation and timing before you visit.
