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By Dr B.C. Gupta, MD · 2026-09-01

Ask the Pathologist - MCQ of the Week. A short question to test how well you know common laboratory tests, with a plain-English explanation from Dr B.C. Gupta, MD (Pathology).

Q. A patient has sudden pain and swelling in the big toe. Which blood test is usually ordered first when gout is suspected?

  • A. Serum Uric Acid
  • B. Serum Ferritin
  • C. Lipid profile
  • D. HbA1c

Answer: A. Serum Uric Acid

Gout happens when uric acid builds up and crystals form in a joint, most often the big toe. A serum uric acid test measures the level of uric acid in the blood and is a common first step when the doctor suspects gout. It is done along with the clinical examination and is interpreted with it, because a high level does not always cause an attack and a normal level does not completely rule gout out.

The sample is a simple blood draw. Fasting is not usually needed for uric acid, though some laboratories ask for preparation, so confirm with the laboratory. Your doctor will explain what the number means and whether further tests or treatment are needed.

If your doctor has asked for a uric acid test, the sample is quick to give. Call the centre to confirm preparation and timing before you visit.

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